London Based

Payton Tung On Yau, PhD

Putting Biology at the Heart of Data Science. I leverage computational power to validate and scale wet-lab intuition, integrating Genomic and Biological data with Reproducible Workflows to ensure results reflect biological reality.

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Recent Focus

Open Source Development

OptSurvCutR currently under peer review at rOpenSci. Standardising survival analysis workflows.

The Resistance Archives

Writing a comprehensive blog series decoding the WHO Top 24 Superbugs. From Pipettes to R Packages.

R

OptSurvCutR

R Package v0.2

Validated biomarker optimisation package. Automating optimal cutpoint determination for survival analysis using information criteria (AIC/BIC).

Dry Lab R / Python / NGS

Computational Genomics

AML Therapeutics: Integrated NanoString & RNA-Seq to validate Tipifarnib MOA.
Bramley Genome: De novo assembly of the heritage cultivar using Nanopore sequencing.
IBD Transcriptomics: Defined gene signatures for mucosal healing.
Translational Science Biobanking / Diagnostics

Molecular Epidemiology

Viral Oncology: Epigenetic profiling of EBV-associated Gastric Cancer.
CRC Diagnostics: Multiplex PCR assays for miRNA & microbial screening.
Pathogenesis: Longitudinal tracking of C. difficile in IBD cohorts.

Biostatistics Textbook

Open Educational Resource

Co-Author of "A Little Bit of Everything in Biostatistics". An applied open-access Jupyter Book for health science students, featuring the Framingham Heart Study & Anorexia Clinical Trial datasets.

Resource Platform

UK Crop Microbiome CryoBank

Previously managed national platforms for UKRI/BBSRC phytobiomes research.

Publications

Research Portfolio

Peer-reviewed findings focusing on Genomic Surveillance, Microbiomes, and Disease Pathology.

Google Scholar ORCID: 0000-0002-6019-3837

Library

Book Cover

Current Read

The Psychology of Money

Morgan Housel
PhD

By Published Works

Biological Nature of Diseases (Medicine)

MBA Candidate

Academic Pedagogy

Mentorship & Roles NTU / UoPeople / DMU / BNU Lecturer & Module Lead across Research Methods and Global Health. Mentoring diverse teams to develop the soft skills required for scientific collaboration and effective communication.
Philosophy Connection & Application Moving beyond knowledge transfer. I focus on connecting people to real-world challenges, fostering an environment where critical thinking drives applied solutions.
Invited Speaker

FOSDEM 2026

"From Binary to Granular: Automating Multi-Threshold Survival Analysis with OptSurvCutR"

Brussels, Belgium

One Health Dynamics

Tracking antimicrobial resistance (AMR) and priority pathogens across the biosphere. My research connects agricultural microbiomes to human epidemiology, mapping how infectious diseases evolve and spill over.

The Hybrid Bridge

"True innovation happens at the intersection. By executing both wet-lab molecular biology and dry-lab computational pipelines, I translate raw genomic data into clinically actionable, reproducible insights."