London Based

Payton Tung On Yau, PhD

Putting Biology at the Heart of Data Science. I leverage computational power to validate and scale wet-lab intuition, integrating Genomic and Biological data with Reproducible Workflows to ensure results reflect biological reality.

Recent Focus

R

OptSurvCutR

R Package v0.2

Validated biomarker optimisation package. Automating optimal cutpoint determination for survival analysis using information criteria (AIC/BIC).

Dry Lab R / Python / NGS

Computational Genomics

AML Therapeutics: Integrated NanoString & RNA-Seq to validate Tipifarnib MOA.
Bramley Genome: De novo assembly of the heritage Bramley cultivar using Oxford Nanopore sequencing.
IBD Transcriptomics: Defined gene signatures for mucosal healing.
Translational Science Biobanking / Diagnostics

Molecular Epidemiology

Viral Oncology: Epigenetic profiling of EBV-associated Gastric Cancer.
CRC Diagnostics: Multiplex PCR assays for miRNA & microbial screening.
Pathogenesis: Longitudinal tracking of C. difficile in IBD cohorts.

One Health: Environment to Medicine

Integrating genomic data from environmental reservoirs and clinical settings. I apply a hybrid wet-dry lens to track emerging pathogens, bridging the communication gap between ecological research and medical diagnostics.

Resource Platform

UK Crop Microbiome CryoBank

Previously managed national platforms for UKRI/BBSRC phytobiomes research.

Publications

Research Portfolio

Peer-reviewed findings focusing on Genomic Surveillance, Microbiomes, and Disease Pathology.

Google Scholar ORCID: 0000-0002-6019-3837

Library

Book Cover

Current Read

The Psychology of Money

Morgan Housel

PhD

By Published Works

Biological Nature of Diseases (Medicine)

MBA Candidate

Academic Pedagogy

Mentorship & Roles NTU / UoPeople / DMU / BNU Lecturer & Module Lead across Research Methods and Global Health. Mentoring diverse teams to develop the soft skills required for scientific collaboration and effective communication.
Philosophy Connection & Application Moving beyond knowledge transfer. I focus on connecting people to real-world challenges, fostering an environment where critical thinking drives applied solutions.
Invited Speaker

FOSDEM 2026

"From Binary to Granular: Automating Multi-Threshold Survival Analysis with OptSurvCutR"

Brussels, Belgium

The Hybrid Bridge

"True innovation happens at the intersection. I execute both Wet Lab biology and Dry Lab computation, connecting environmental surveillance with clinical medicine to drive reproducible science."